Correction: Type I Interferon: Potential Therapeutic Target for Psoriasis?
نویسندگان
چکیده
منابع مشابه
Type I Interferon: Potential Therapeutic Target for Psoriasis?
BACKGROUND Psoriasis is an immune-mediated disease characterized by aberrant epidermal differentiation, surface scale formation, and marked cutaneous inflammation. To better understand the pathogenesis of this disease and identify potential mediators, we used whole genome array analysis to profile paired lesional and nonlesional psoriatic skin and skin from healthy donors. METHODOLOGY/PRINCIP...
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Our group recently described a population of antigen-presenting cells that appear to be critical in psoriasis pathogenesis, termed inflammatory myeloid dendritic cells (CD11c(+)/blood dendritic cell (DC) antigen 1(-)). Triggering receptor expressed on myeloid cells type-1 (TREM-1) signaling was a major canonical pathway in the published transcriptome of these cells. TREM-1 is a member of the Ig...
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The outcome of a viral infection reflects the balance between virus virulence and host susceptibility. The clone 13 (Cl13) variant of lymphocytic choriomeningitis virus--a prototype of Old World arenaviruses closely related to Lassa fever virus--elicits in C57BL/6 and BALB/c mice abundant negative immunoregulatory molecules, associated with T-cell exhaustion, negligible T-cell-mediated injury, ...
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The IL-1R/TLR family has been receiving considerable attention as potential regulators of inflammation through their ability to act as either activators or suppressors of inflammation. Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, allergic inflammation, elevated serum total, allergen-specific IgE levels, and increased Th2 cytokine production. The discover...
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W e read with great interest the article by Rheinheimer and cols. (1), showing that four hundred and eighty six patients with type 1 diabetes (T1D) and 484 nondiabetic subjects were conducted to discuss the rs1893217 (T/C) polymorphism in protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) gene for T1D from Southern Brazil, by which the C allele was observed in 14.5% of the T1D patie...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/annotation/fbcbcab9-2e87-4ec7-af6e-c6e9e64ad4b3